Bromadiolone is a rodenticide meant to kill rats and mice. Anticoagulants like bromadiolone work by preventing the blood from clotting. Unlike some other rat poisons, which require multiple days of feeding by an animal, bromadiolone can be lethal from one day's feeding. Bromadiolone was first registered in the United States in
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Bromadiolone is a potent anticoagulant rodenticide. It is a second-generation 4-hydroxycoumarin derivative and vitamin K antagonist , often called a "super- warfarin " for its added potency and tendency to accumulate in the liver of the poisoned organism.
When first introduced to the UK market in , it was effective against rodent populations that had become resistant to first generation anticoagulants. Bromadiolone can be absorbed through the digestive tract, through the lungs, or through skin contact. The pesticide is generally given orally. The lack of vitamin K in the circulatory system reduces blood clotting and will cause death due to internal hemorrhaging.
Poisoning does not show effects for 24 to 36 hours after it is eaten and can take up to 2—5 days to cause death. Following are acute LD 50 values for various animals mammals : .
The compound is used as a mixture of four stereoisomers. Its two stereoisomeric centers are at the phenyl- and the hydroxyl-substituted carbons in the carbon chain of the substituent at the 3 position of the coumarin. Vitamin K1 is used as antidote. From Wikipedia, the free encyclopedia. This article needs additional citations for verification. Please help improve this article by adding citations to reliable sources.
Unsourced material may be challenged and removed. CAS Number. Interactive image. PubChem CID. Chemical formula. Government Printing Office. Archived from the original PDF on February 25, Retrieved October 29, Archived from the original PDF on Retrieved Pest control : Rodenticides. Warfarin Coumatetralyl. Brodifacoum Bromadiolone Difenacoum Flocoumafen. Chlorophacinone Pindone Diphacinone. Crimidine Phenylsilatrane Strychnine Tetramethylenedisulfotetramine Chlorophenylsilatrane.
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