It causes damage to your blood vessels that can lead to sores in the mouth, rashes, and other symptoms. The severity of the disease varies from person to person. Symptoms may temporarily go into remission, only to return at a later time. Symptoms can be managed with medication and lifestyle changes.
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This system, which normally protects the body against infections by producing controlled inflammation, becomes over-active and results in unpredictable outbreaks of unwanted and exaggerated inflammation. This extra inflammation particularly affects blood vessels of all sizes, including arteries and veins. As a result, symptoms occur wherever there is a patch of inflammation; this can be anywhere where there is a blood supply — from the brain down to the feet. It is not because of any known infections, it is not necessarily hereditary, but can sometimes run in families, and it is not thought to be related to lifestyle, age, or where someone has lived or where they have been on holiday.
It is not associated with cancer, but is found more frequently in people with certain tissue-type molecules and genes, also the potential link with this is not understood. It does not follow the usual pattern for autoimmune diseases and is better considered, for now, as a disease of inflamed blood vessels vasculitis — a vasculitic disease.
There are several ways in which the immune system can be suppressed to an appropriate level to reduce the extra inflammation, and this suppresses the symptoms.
Most of the symptoms are painful but not life-threatening. However, when the disease affects major parts of the body, such as the eyes or brain, it can cause serious consequences including blindness or strokes — but this is fortunately rare. The disease can often, but not always, become less severe with increasing age, where flare-ups become less aggressive and happen less frequently. It much more common in the Middle East and Asia. As yet, it is not known what triggers this disease.
Endovascular treatment for Behçet’s disease: a case report
Cardiovascular involvement has been thoroughly described in the literature and the major cause of death in BD is secondary to aneurysm complications. In this case report, a patient with BD presented with a recurrent abdominal aortic aneurysm, which was corrected using a custom-made endoprosthesis. The optimal treatment for patients with BD remains highly controversial and challenging because of technical difficulties and frequent recurrence. Endovascular intervention seems to be a feasible alternative with considerably less morbidity than conventional surgery. The disease is most prevalent among men aged 20 to 40 years and is generally seen in Mediterranean countries, the Middle East, and Japan, but it has been described worldwide.
What is Behçet’s?
The cause is unknown. There is no cure. Inflammatory eye disease can develop early in the disease course and lead to permanent vision loss in 20 percent of cases. Ocular involvement can be in the form of posterior uveitis , anterior uveitis , or retinal vasculitis. Anterior uveitis presents with painful eyes, conjuctival redness, hypopyon , and decreased visual acuity, while posterior uveitis presents with painless decreased visual acuity and visual field floaters. A rare form of ocular eye involvement in this syndrome is retinal vasculitis which presents with painless decrease of vision with the possibility of floaters or visual field defects.