HANDBOOK OF OPTOFLUIDICS PDF

Optofluidics is an emerging field that involves the use of fluids to modify optical properties and the use of optical devices to detect flowing media. Ultimately, its value is highly dependent on the successful integration of photonic integrated circuits with microfluidic or nanofluidic systems. Handbook of Optofluidics provides a snapshot of the state of the field, captures current trends, and gives insight into the technology of tomorrow, which will enable researchers to tackle challenges and opportunities that it can uniquely answer. Divided into three sections, this comprehensive resource begins by introducing the scientific foundations that contribute to optofluidics.

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Handbook of Photonics for Biomedical Engineering pp Cite as. Optofluidic lab-on-a-chip LOC devices have drawn significant attention because of their special attraction to point-of-care applications. In this chapter, the advancement and key accomplishments of LOC devices that utilize optics as means to detect biomedical signals are discussed. The topics being covered include optofluidic waveguide designs, detection techniques, and various optofluidic LOC systems and experimental demonstration.

Limited by the fabrication and material issues, most LOC devices produce lower signal quality than their large-size counterparts. Therefore, improving the signal quality and detection sensitivity of LOC devices is of tremendous importance to find their clinical applications.

To this end, novel techniques that combine the optical-coding method with 3-D flow confinement designs are discussed. The optical-coding method enables us to use digital signal processing to enhance the signal-to-noise ratio, while the 3-D flow focusing designs help reduce variations in cell distribution inside the channel, thus removing some major sources of signal fluctuations.

Besides a review of key efforts and accomplishments in the field, this chapter also points out promising pathways toward low-cost, high-performance optofluidic LOC systems for point-of-care clinics.

Skip to main content. This service is more advanced with JavaScript available. Advertisement Hide. Living reference work entry First Online: 06 October This is a preview of subscription content, log in to check access. Nature — CrossRef Google Scholar. Biomicrofluidics CrossRef Google Scholar. Analyst — CrossRef Google Scholar. Godin J, Lo YH Two-parameter angular light scatter collection for microfluidic flow cytometry by unique waveguide structures.

Pamme N, Koyama R, Manz A Counting and sizing of particles and particle agglomerates in a microfluidic device using laser light scattering: application to a particle-enhanced immunoassay.

Godin J, Lien V, Lo Y Integrated fluidic photonics for multi-parameter in-plane detection in microfluidic flow cytometry. Liedberg B, Lundstrom I, Stenberg E Principles of biosensing with an extended coupling matrix and surface-plasmon resonance. Kretschmann E, Kroger E Reflection and transmission of light by a rough surface, including results for surface-plasmon effects.

Appl Phys Lett Google Scholar. Gao XH, Nie SM Quantum dot-encoded mesoporous beads with high brightness and uniformity: rapid readout using flow cytometry. Chun B, Ladd AJC Inertial migration of neutrally buoyant particles in a square duct: an investigation of multiple equilibrium positions.

Chu F, Wang LP Applications of support vector machines to cancer classification with microarray data. Wang L Support vector machines: theory and applications. Springer, New York Google Scholar. Simonnet C, Groisman A Two-dimensional hydrodynamic focusing in a simple microfluidic device. Yang R, Feeback DL, Wang W Microfabrication and test of a three-dimensional polymer hydro-focusing unit for flow cytometry applications.

Testa G, Bernini R Integrated tunable liquid optical fiber. Personalised recommendations. Cite entry How to cite? ENW EndNote.

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Handbook of Optofluidics

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